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DUTCH Complete™

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DUTCH Complete™

Original price was: $499.00.Current price is: $397.00. - Free Shipping

Advanced hormone test, offering an extensive profile of sex and adrenal hormones and melatonin, along with their metabolites, to identify symptoms of hormonal imbalances.

At-home test: urine collection

Who should take this test?

If you suffer from any of these symptoms, this test may be right for you.

brain fog
developmental delays
Night sweats
Headaches
Sleep problems
Mood swings
Difficulty concentrating
Stress
Memory lapse
Fatigue and weakness
Depression
Anxiety
Hot flashes

Description

DUTCH Complete™ Urine Test

Our flagship product. The DUTCH Complete™ is the most advanced hormone test, offering an extensive profile of sex and adrenal hormones and melatonin, along with their metabolites, to identify symptoms of hormonal imbalances. Easily collected in the comfort of your own home, samples are then sent to our lab to be processed. The DUTCH Complete™ is the most accurate test providing a complete assessment of hormonal health.

The kit includes:

  • Easy directions and filter paper collection strips
  • Requisition form for patient information, pertinent supplements, medications, hormone replacement and a health questionnaire
  • Sealable return envelope

The results include:

  • Analysis of 35 different hormones: estrogen, progesterone, testosterone, DHEA-S, and cortisol along with their metabolites
  • Daily free cortisol patterns to provide insight into adrenal insufficiency or symptoms of chronic stress
  • Graphical representation of results and embedded video tutorials to assist in the hormone assessment to share with your medical provider
  • DUTCH OATs: Oxidative stress marker – 8-Hydroxy-2-deoxyguanosine (8-OHdG), melatonin (6-OHMS), and six organic acid tests (OATs) including markers for vitamin B12 (methylmalonate), vitamin B6 (xanthurenate), kynurenate, glutathione (pyroglutamate), dopamine (homovanillate), norepinephrine/epinephrine (vanilmandelate).

View Sample Report

Markers Measured

DUTCH Complete™ markers measured:

Sex Hormones Panel

  • a-Pregnanediol
  • b-Pregnanediol
  • DHEA-S
  • Androsterone
  • Etiocholanolone
  • Testosterone
  • 5a-DHT
  • 5a-Androstanediol
  • 5b-Androstanediol
  • Epi-Testosterone
  • Estrone (E1)
  • Estradiol (E2)
  • Estriol (E3 aka 16-OHE2)
  • 2-Hydroxyestrone (2-OHE1)
  • 4-Hydroxyestrone (4-OHE1)
  • 16-Hydroxyestrone (16-OHE1)
  • 2-Methoxyestrone (2-MeOE1)
  • 2-Hydroxyestradiol (2-OH-E2)
  • 4-Hydroxyestradiol (4-OH-E2)

Adrenal Panel

  • Diurnal Pattern of Free Cortisol
  • Diurnal Pattern of Free Cortisone
  • a-Tetrahydrocortisol (a-THF)
  • b-Tetrahydrocortisol (b-THF)
  • b-Tetrahydrocortisone (b-THE)
  • Metabolized Cortisol (THF+THE)

Organic Acids Test (OATS) Panel

  • Dopamine (Homovanillate or HVA)
  • Norepinephrine/Epinephrine (Vanilmandelate or VMA)
  • Vitamin B6 (Kynurenate or KYNA)
  • Vitamin B6 (Xanthurenate)
  • Vitamin B12 (Methylmalonate or MMA)
  • Glutathione (Pyroglutamate)
  • Neuroinflammation (Quinolinate)
  • Gut Health (Indican)
  • Biotin (b-Hydroxyisovalerate)
  • 8-OHdG (8-Hydroxy-2-deoxyguanosine)
  • Melatonin (6-OH-Melatonin-Sulfate)

Symptoms

Hormone and Oranic Acid Imbalance Symptoms

Conditions and symptoms associated with hormonal and organic acid imbalances include:

  • Mental and/or developmental delays
  • Night sweats
  • Headaches
  • Sleep problems
  • Mood swings
  • Difficulty concentrating
  • Stress
  • Memory lapse
  • Fatigue and weakness
  • Depression and/or anxiety
  • Hot flashes
  • Dizziness
  • Nausea
  • Sugar cravings
  • Low libido
  • Weight gain
  • Poor stamina
  • Decreased muscle mass/strength
  • Neck/back pain
  • Decreased urinary flow (men)
  • Erectile dysfunction
  • Chronic Irritability
  • Increased facial hair/acne
  • Irregular menstrual cycles
  • Thinning hair, eyebrows, or eyelashes

About Test

About DUTCH Complete™

Key Details

  • Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
  • This is a urine collection kit that you will collect for at home.

What Days of the Month Do I Collect?

  • Cycling Premenopausal Women
    • Begin collection between days 19 and 22 of a 28-day cycle. For longer cycles, add the number of days you usually go beyond 28 days. In a similar manner, subtract if your cycles are shorter (example: collect days 17-20 for a 26 day cycle)
    • For irregular cycles or non-cycling (ablation or uterus removed), watch the irregular cycle collection video in the video library at dutchtest.com/videos for suggestions on collecting.
  • Men & Non-Cycling or Postmenopausal Women
    • Collect any day.

Restrictions

  • Watch Your Fluid Consumption
    • No Alcohol, Caffeine or Large Fluid Intake after lunch before collecting the dinner sample. No more than one cup of fluids between Samples #3 and #4.
    • Do not drink any fluids for two hours before collecting each sample. We suggest you keep fluids to < 32oz on day 1, and < 8oz between waking (Sample #3) and 2-hrs after waking (Sample #4).
  • Using Hormones?
    • DO NOT TAKE oral DHEA 48 hours before, or any oral estrogen* or pregnenolone 72 hours before your first collection.
    • Do not skip doses of birth control for this test unless instructed by your practitioner.
    • Any other hormones taken at NIGHT (including oral progesterone) should be taken after the bedtime sample. Generally, hormone creams or gels can be taken as usual during the test. All hormones taken in the MORNING should not be taken until after sample #4.
      If you take glucocorticoids (Prednisone, Dexamethasone, etc.) check with your practitioner. For patches, pellets and injections, collect midway between doses. If you take sublingual hormones (absorbed in the mouth or under the tongue) or if you take oral hydrocortisone (cortisol), visit dutchtest.com for specific video instructions.
  • Foods
    • Avoid avocado, bananas and fava beans for 48 hours before collecting as they may elevate the HVA organic acid result; if you do consume, please make a note on your requisition form.
  • Supplements
    • Some supplements may impact the HVA organic acid result. If you take any of the following, please consult your provider: Tyrosine, L-Dopa, D,L-Phenylalanine (DLPA), Mucuna and Quercetin.

When to Collect

While adhering to your most common wake/sleep schedule, collect as close as possible to the below timeline.

Collection Day 1

  • Sample #1: Dinnertime
    • Approximately 5pm. Do not drink fluids for two hours before collecting.
  • Sample #2: Bedtime
    • Approximate 10pm. Do not drink fluids for two hours before collecting.

Collection Day 2

  • Extra Overnight Sample
    • Collect at your first waking sleep disturbance with urination*
    • *If you wake and urinate a second time during the night, do not collect.
  • Sample #3: Wake/Rising
    • Within 10 minutes; Do not lay awake in bed before Sample #3.
  • Sample #4: 2-hrs After Waking
    • Tip: Set a timer after Sample #3

How to Collect

  • Complete all information on each collection device.
  • Saturate the filter paper by urinating directly on it OR use a clean cup and dip the filter paper.
  • Leave the collection device open to dry for at least 24 hours.
  • Once dry, close each collection device. Place all devices in the resealable plastic bag and return in the provided envelope. Be sure to include the completed requisition form (required) and the payment card (if needed).

Why Use DUTCH?

The Easiest Patient Collection

Patients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship worldwide.

Analytical and Clinical Validation

Precision Analytical’s testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing. See the data on the next page to support the analytical and clinical validation of this powerful new testing model.

Effective HRT Monitoring

DUTCH testing was designed to be optimally effective for most forms of hormone replacement therapy. Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.

How does DUTCH Compare to Other Hormone Tests?

DUTCH vs. Saliva Testing

While the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.

DUTCH vs. Serum Testing

While the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).

DUTCH vs. 24-Hour Urine Testing

There are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.

FAQ

Frequently Asked Questions

What if I miss a collection?

Simply collect the sample as instructed the following day. All samples do not need to be collected in one 24-hour period.

Do I have to take the samples in the order listed?

No, they can be collected in a different order. If you wish you may start with sample #3, followed by #4, #1 & #2. If you begin with #3, collect the extra sample if you wake and urinate in the night.

How long can I keep the dried samples before sending them in?

While hormone levels are very stable in dried samples, they should be sent back as soon as possible. If you have to wait to send them in, place in freezer (in plastic bag) after drying.

Do I need to stop taking my hormones for this test?

This test is built to test patients “on” their hormones. Our suggestion is to follow the Hormone Schedule (listed previously), and any  specific instructions given by your provider.

What if my sleep schedule is abnormal (night workers, etc.)?

Collect the bedtime sample (#2) before your longest stretch of sleep, the waking sample (#3) after this sleeping period, and sample #4 two hours later. The dinnertime sample (#1) should be collected 4-7 hours before bed.

What if I am unable to urinate at the specific time?

Simply drink some fluids and go as soon as you are able.

Is DUTCH testing appropriate for children?

The minimum age for testing is 12 years old. To test children under 12, we strongly recommend the DUTCH Cortisol Awakening Response (CAR) measured with saliva.

How It Works

1

Order your test

You'll get an email confirmation from us.

2

Within 48 hours of payment

The lab will confirm your order and provide tracking.

3

2 days after kits ship

We will send you test instructions.

4

When results are in

You'll be notified via email, with instructions to access via secured portal.

5

Interpretation

Learn how to read your lab report.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

*Regulatory Statement*
Vibrant testing does not demonstrate absolute positive and negative predictive values for any disease state or condition. Its clinical utility has not been fully established. Vibrant validates the accuracy and precision of the testing but not of its clinical or diagnostic value. So these tests are for wellness and informational purpose only. Vibrant is actively doing clinical research on these samples, de-identified from patients under an IRB and will make research publications towards the same as and when the clinical utility is well established. These tests have been laboratory developed and their performance characteristics determined by Vibrant America LLC, a CLIA-certified laboratory performing the test CLIA#:05D2078809. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. The general wellness test intended uses relate to sustaining or offering general improvement to functions associated with a general state of health while making reference to diseases or conditions. Content provided for informational purposes only and should not be construed as medical advice. Content provided to help you make a healthy lifestyle, dietary, and treatment choices in consultation with your healthcare provider. It is intended to be used as a tool to encourage a general state of health and well-being. Please consult with your healthcare practitioner for diagnosis and treatment considerations. The Vibrant Wellness platform provides tools for you to track and analyze your general wellness profile.