Join Insider Club FREE

I Want In! Already a member? Login

Adrenal Fatigue

Adrenal Fatigue

$247.00 - Free Shipping

To assess the status of adrenal fatigue through diurnal cortisol mapping and assess their precursors and metabolites.

Salivary hormone test to assess for Adrenal Fatigue. Includes a full panel of hormones: 4-point cortisol collection, DHEA, cortisone, testosterone and estrogen, so you can see your full diurnal cortisol and hormone pattern and their precursors and metabolites.

Why am I so tired?

You may be experiencing a cortisol issue. Test interpretation and educational recommendations are included with your results.

At-home test: saliva collection

Who should take this test?

If you suffer from any of these symptoms, this test may be right for you.

Hot flashes
Night sweats
Poor sleep
Low libido
Memory lapse


Adrenal Fatigue Salivary Test

Adrenal Fatigue Sample Report

Hormones are essential chemical messengers which regulate routine processes in the body. Hormone imbalances can affect a wide range of body functions including:

  • metabolism and appetite,
  • heart rate
  • sleep cycles
  • reproductive cycles and sexual function
  • general growth and development
  • mood and stress levels
  • body temperature

All of these can negatively affect quality of life and may increase the risk for hormone-related diseases, including hormone-sensitive cancers.

A comprehensive assessment of individual hormones would provide patterns of imbalances in different hormones, while assessment of their metabolites would provide beneficial information on affected downstream pathways. This would help to treat underlying causes of hormone imbalances and identify disease risks associated with individual hormone metabolites.

Assessment of sex and adrenal hormones is critical to differentiate hormonal imbalance from other common conditions which have overlapping symptoms, such as: chronic infections, toxic exposures, GI malabsorption, hepatic detoxification problems, and metabolic disorders.

Hormones, especially adrenal hormones and sex hormones, are interconnected with neurotransmitters. An imbalance in adrenal and sex hormones could lead to neurotransmitter imbalances which could revert back to cause hormonal imbalances. Consider running a Vibrant Hormones panel alongside a Neurotransmitters panel for the most accurate assessment of causes of hormone imbalances and their connected neurotransmitter pathways.

The Vibrant Hormones panel is the most comprehensive panel available to assess the status of hormones in the human body. It eliminates the guesswork of determining root causes of generic and global symptoms and provides practitioners with a clear-cut picture of hormonal imbalances present.

Markers Measured

Adrenal Fatigue Salivary Test markers measured:

Saliva Hormones

  • Estradiol (E2)
  • Estrone (E1)
  • Estriol (E3)
  • E3/(E1+E2) Ratio
  • Progesterone (Pg)
  • Pg/E2 Ratio
  • Testosterone
  • DHEA-S
  • 4 Point Cortisol Cycling
  • 4 Point Diurnal Cortisol Mapping
  • 4 Point Diurnal Cortisone Mapping
  • Cortisone


Adrenal Fatigue Symptoms

Conditions and symptoms associated with hormonal imbalances include:

  • Hot flashes
  • Night sweats
  • Headaches
  • Headaches
  • Poor sleep
  • Anxiety
  • Depression
  • Stress
  • Low libido
  • Memory lapse
  • Sugar cravings
  • Weight gain
  • Dry, dull appearance of skin
  • Poor stamina
  • Decreased muscle mass/strength
  • Neck/back pain
  • Decreased urinary flow (men)
  • Erectile dysfunction
  • Apathy/mood changes
  • Poor cognition
  • Brain fog
  • Fatigue
  • Chronic Irritability
  • Increased facial hair/acne
  • Irregular menstrual cycles
  • Thinning hair, eyebrows, or eyelashes

About Test

About Adrenal Fatigue Test

Key Details

  • Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
  • This is a salivary (saliva) collection kit that you will collect for at home.
  • If you are a menstruating woman, you should collect your samples on specific days of your cycle.
  • If you are taking hormones, you should collect your samples at specific intervals after dosing.
  • Do not brush your teeth, eat, or drink anything but water for 2-3 hours before each saliva sample collection.
  • Ship samples back to the lab as soon as possible. 

Preparation & Timing

  • For 2-3 hours prior to each saliva sample collection, 
    • Do not brush your teeth.
    • Do not eat.
    • Fast for 2-3 hours prior to each collection to ensure accurate cortisol measurements. Do not drink anything but water.
  • If you miss a collection timing, collect at the same time the next day and label appropriately.
  • If you are a menstruating woman, collect samples on the days indicated below:
    • Regular cycles: For a 28-day cycle, collect on Day 19, 20, or 21 of your cycle.
      • Day 1 is the first day of your period.
    • Irregular cycles: Collect 5 days before your period begins.
    • Unpredictable cycles: Collect any day when not bleeding.
  • If you are taking topical or oral (pill) hormones,
    • Do not take within 12 hours of sample collection.
  • If you are taking sublingual or troche hormones, 
    • Consult your healthcare provider. This test is not recommended for you, as these therapies may cause false salivary hormone results.
  • If you have hormone patches, vaginal rings, hormone pellets, or injectable hormones, 
    • Collect your samples halfway between doses.
  • If you are using steroids, consult your healthcare provider regarding the timing of this test.
  • 3 days prior to sample collection
    • Avoid using any anti-aging products.
    • Avoid using vaginal hormones.

Requisition & Payment

  • Forms Included with your kit:
    • Requisition form: Confirm your information is correct on this form.
      • Since your kit has been prepaid, you do not need to fill in the payment information on any of these forms.
  • Use the prepaid FedEx shipping envelope to send this back to the lab as soon as possible, Monday - Friday only. 

The Vibrant Experience

Vibrant America is a leading science and technology company delivering life-transforming laboratory services using an integrated microarray platform that enables multiplex testing at an affordable cost.

Vibrant’s relationship with its patients and providers is special. We go out of our way to provide the value and resources our providers need to accurately interpret test results and give patients the most accurate health information.

The Most Accurate In the Industry

All tests run on Vibrant’s proprietary 3Dense microchip technology platform boast an unrivaled specificity and sensitivity – which translates to the highest standard of accuracy of results in the lab industry.

Our Lab Technology

Vibrant America is at the forefront of modern medicine. Our technology was developed out of passion for better medicine, and we believe that automation is the key to high-quality and accurate test results. Multiplexing tests on a single sample enable a fast turnaround time.

Our Mission

Dedicated to bring clinically relevant test at a rapid pace to enable affordable high-quality diagnostics to every individual.

  • High-quality lab service
  • Fully automated systems
  • Low cost
  • Fast Turn Around Time

Quality and Security

All of our laboratory testings is done in a CLIA and CAP-certified laboratory in California.

Vibrant America's Compliance Overview

How It Works


Order your test

You'll get an email confirmation from us.


Within 48 hours of payment

The lab will confirm your order and provide tracking.


2 days after kits ship

We will send you test instructions.


When results are in

You'll be notified via email, with instructions to access via secured portal.



Learn how to read your lab report.

You may also like…

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

*Regulatory Statement*
Vibrant testing does not demonstrate absolute positive and negative predictive values for any disease state or condition. Its clinical utility has not been fully established. Vibrant validates the accuracy and precision of the testing but not of its clinical or diagnostic value. So these tests are for wellness and informational purpose only. Vibrant is actively doing clinical research on these samples, de-identified from patients under an IRB and will make research publications towards the same as and when the clinical utility is well established. These tests have been laboratory developed and their performance characteristics determined by Vibrant America LLC, a CLIA-certified laboratory performing the test CLIA#:05D2078809. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. The general wellness test intended uses relate to sustaining or offering general improvement to functions associated with a general state of health while making reference to diseases or conditions. Content provided for informational purposes only and should not be construed as medical advice. Content provided to help you make a healthy lifestyle, dietary, and treatment choices in consultation with your healthcare provider. It is intended to be used as a tool to encourage a general state of health and well-being. Please consult with your healthcare practitioner for diagnosis and treatment considerations. The Vibrant Wellness platform provides tools for you to track and analyze your general wellness profile.