Measures 32 common SNPs and 16 markers of oxidative damage to assess your genetic ability to manage oxidative stress, as well as your current stress status.
Oxidative stress is an imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the body’s antioxidant defenses, which can’t effectively neutralize these reactive compounds. Excessive oxidation can actively harm critical cellular components such as lipids, DNA, RNA, and proteins, which are the building blocks of the human body.
Vibrant Oxidative stress is a comprehensive and advanced test that measures 16 oxidative damage markers to your DNA, RNA, protein, Lipids and 32 genetic variants to personalize your genetic disposition to Antioxidant enzymes.
The Oxidative Stress Profile measures 32 common SNPs and 16 markers of oxidative damage to assess your genetic ability to manage oxidative stress, as well as your current stress status.
Oxidative stress poses a threat to longevity as it is implicated in the development of various diseases.
This state of stress can create a detrimental cycle where one condition exacerbates another, leading to further health complications.
By understanding your oxidative stress, your provider can tailor treatment strategies to address potential weaknesses in the oxidative stress system, reduce buildup of ROS, and promote better health and longevity.
With this comprehensive profile, you can better understand your ability to manage oxidative stress and specific antioxidant needs and create personalized wellness plans tailored to your genetics.
Markers Measured
Oxidative Stress Profile markers measured:
Genes
rs2796498 PRKAA2
rs10789038 PRKAA2
rs1001179 CAT
rs7943316 CAT
rs4756146 CAT
rs20417 COX-2
rs916321 CYB5R3
rs1048943 CYP1A1
rs10911021 GLUL
rs1050450 GPX1
rs1987628 GPX1
rs4902346 GPX2
rs2071566 GPX2
rs713041 GPX4
rs366631 GSTM1
rs3754446 GSTM5
rs1695 GSTP1
rs121909307 GSS
rs8190955 GSR
rs2071746 HMOX1
rs4673 CYBA
rs9932581 CYBA
rs3877899 SELENOP
rs2234694 SOD1
rs4880 SOD2
rs1799895 SOD3
rs8192287 SOD3
rs7310505 TXNRD1
rs1548357 TXNRD2
rs4485648 TRXR2
rs206812 XDH
rs2073316 XDH
Lipid Peroxidation
Malondialdehyde
Glutathione 4-hydroxynonenal (GS-HNE)
8-iso-prostaglandin F2α (8-iso-PGF2α)
11-β-Prostaglandin F2α
15(R)-Prostaglandin F2α
DNA Damage
8-Hydroxy-2-deoxyguanosine (8-OHdG)
8-Hydroxyguanine
8-Hydroxyguanosine
Protein Oxidation
Dityrosine
3-Bromotyrosine
3-Chlorotyrosine
Nitrative Stress Biomarkers
8-Nitroguanosine
8-Nitroguanine
Nitrotyrosine
Advanced Glycation Products
Nε-(carboxymethyl) lysine (CML)
Nε-carboxyethyllysine (CEL)
Symptoms
Oxidative Stress Symptoms
Cancer
Cardiovascular disease
Neurological conditions such as Alzheimer's
Respiratory disease
Rheumatoid arthritis
Kidney disease
About Test
About Oxidative Stress Profile Test
SALIVA COLLECTION
Key Details
Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
This is a salivary (saliva) collection kit that you will collect for at home.
Do not brush your teeth, eat, or drink anything but water for 2-3 hours before each saliva sample collection.
Ship samples back to the lab as soon as possible.
Preparation & Timing
No eating a major meal within 60 minutes of sample collection.
Avoid foods with high sugar or acidity, or high caffeine content, immediately before sample collection
Rinse mouth with water to remove food residue and waiting at least 10 minutes after rinsing to avoid sample dilution before collecting saliva.
Passive drool - allowing saliva to naturally pool in mouth and then spit. Repeat this process to fill required saliva. Do not simulate saliva collection.
URINE COLLECTION
Key Details
Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
This is a urine collection kit that you will collect for at home.
Do not collect samples while menstruating.
Do not drink more than 8 oz water 1 hour prior to urine collection.
Use FedEx to ship samples back to the lab as soon as possible, Monday - Friday only.
Preparation & Timing
Do not collect samples while menstruating.
Fasting is not required. However, fasting for 24 hours may increase the excretion of toxic chemicals.
Please consult your healthcare practitioner prior to fasting.
Do not drink more than 8 oz water 1 hour prior to urine collection.
Requisition & Payment
Forms Included with your kit:
Requisition form: Confirm your information is correct on this form.
Since your kit has been prepaid, you do not need to fill in the payment information on any of these forms.
Use the prepaid FedEx shipping envelope to send this back to the lab as soon as possible, Monday - Friday only.
The Vibrant Experience
Vibrant America is a leading science and technology company delivering life-transforming laboratory services using an integrated microarray platform that enables multiplex testing at an affordable cost.
Vibrant’s relationship with its patients and providers is special. We go out of our way to provide the value and resources our providers need to accurately interpret test results and give patients the most accurate health information.
The Most Accurate In the Industry
All tests run on Vibrant’s proprietary 3Dense microchip technology platform boast an unrivaled specificity and sensitivity – which translates to the highest standard of accuracy of results in the lab industry.
Our Lab Technology
Vibrant America is at the forefront of modern medicine. Our technology was developed out of passion for better medicine, and we believe that automation is the key to high-quality and accurate test results. Multiplexing tests on a single sample enable a fast turnaround time.
Our Mission
Dedicated to bring clinically relevant test at a rapid pace to enable affordable high-quality diagnostics to every individual.
High-quality lab service
Fully automated systems
Low cost
Fast Turn Around Time
Quality and Security
All of our laboratory testings is done in a CLIA and CAP-certified laboratory in California.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
*Regulatory Statement*
Vibrant testing does not demonstrate absolute positive and negative predictive values for any disease state or condition. Its clinical utility has not been fully established. Vibrant validates the accuracy and precision of the testing but not of its clinical or diagnostic value. So these tests are for wellness and informational purpose only. Vibrant is actively doing clinical research on these samples, de-identified from patients under an IRB and will make research publications towards the same as and when the clinical utility is well established. These tests have been laboratory developed and their performance characteristics determined by Vibrant America LLC, a CLIA-certified laboratory performing the test CLIA#:05D2078809. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. The general wellness test intended uses relate to sustaining or offering general improvement to functions associated with a general state of health while making reference to diseases or conditions. Content provided for informational purposes only and should not be construed as medical advice. Content provided to help you make a healthy lifestyle, dietary, and treatment choices in consultation with your healthcare provider. It is intended to be used as a tool to encourage a general state of health and well-being. Please consult with your healthcare practitioner for diagnosis and treatment considerations. The Vibrant Wellness platform provides tools for you to track and analyze your general wellness profile.
