Description
Oxidative Stress Profile Saliva and Urine Test
Oxidative stress is an imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the body’s antioxidant defenses, which can’t effectively neutralize these reactive compounds. Excessive oxidation can actively harm critical cellular components such as lipids, DNA, RNA, and proteins, which are the building blocks of the human body.
Vibrant Oxidative stress is a comprehensive and advanced test that measures 16 oxidative damage markers to your DNA, RNA, protein, Lipids and 32 genetic variants to personalize your genetic disposition to Antioxidant enzymes.
This profile includes these panels:
Why is This Test Important?
- The Oxidative Stress Profile measures 32 common SNPs and 16 markers of oxidative damage to assess your genetic ability to manage oxidative stress, as well as your current stress status.
- Oxidative stress poses a threat to longevity as it is implicated in the development of various diseases.
- This state of stress can create a detrimental cycle where one condition exacerbates another, leading to further health complications.
- By understanding your oxidative stress, your provider can tailor treatment strategies to address potential weaknesses in the oxidative stress system, reduce buildup of ROS, and promote better health and longevity.
- With this comprehensive profile, you can better understand your ability to manage oxidative stress and specific antioxidant needs and create personalized wellness plans tailored to your genetics.
Markers Measured
Oxidative Stress Profile markers measured:
Genes
- rs2796498 PRKAA2
- rs10789038 PRKAA2
- rs1001179 CAT
- rs7943316 CAT
- rs4756146 CAT
- rs20417 COX-2
- rs916321 CYB5R3
- rs1048943 CYP1A1
- rs10911021 GLUL
- rs1050450 GPX1
- rs1987628 GPX1
- rs4902346 GPX2
- rs2071566 GPX2
- rs713041 GPX4
- rs366631 GSTM1
- rs3754446 GSTM5
- rs1695 GSTP1
- rs121909307 GSS
- rs8190955 GSR
- rs2071746 HMOX1
- rs4673 CYBA
- rs9932581 CYBA
- rs3877899 SELENOP
- rs2234694 SOD1
- rs4880 SOD2
- rs1799895 SOD3
- rs8192287 SOD3
- rs7310505 TXNRD1
- rs1548357 TXNRD2
- rs4485648 TRXR2
- rs206812 XDH
- rs2073316 XDH
Lipid Peroxidation
- Malondialdehyde
- Glutathione 4-hydroxynonenal (GS-HNE)
- 8-iso-prostaglandin F2α (8-iso-PGF2α)
- 11-β-Prostaglandin F2α
- 15(R)-Prostaglandin F2α
DNA Damage
- 8-Hydroxy-2-deoxyguanosine (8-OHdG)
- 8-Hydroxyguanine
- 8-Hydroxyguanosine
Protein Oxidation
- Dityrosine
- 3-Bromotyrosine
- 3-Chlorotyrosine
Nitrative Stress Biomarkers
- 8-Nitroguanosine
- 8-Nitroguanine
- Nitrotyrosine
Advanced Glycation Products
- Nε-(carboxymethyl) lysine (CML)
- Nε-carboxyethyllysine (CEL)
About Test
About Oxidative Stress Profile Test
SALIVA COLLECTION
Key Details
- Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
- This is a salivary (saliva) collection kit that you will collect for at home.
- Do not brush your teeth, eat, or drink anything but water for 2-3 hours before each saliva sample collection.
- Ship samples back to the lab as soon as possible.
Preparation & Timing
- No eating a major meal within 60 minutes of sample collection.
- Avoid foods with high sugar or acidity, or high caffeine content, immediately before sample collection
- Rinse mouth with water to remove food residue and waiting at least 10 minutes after rinsing to avoid sample dilution before collecting saliva.
- Passive drool - allowing saliva to naturally pool in mouth and then spit. Repeat this process to fill required saliva. Do not simulate saliva collection.
URINE COLLECTION
Key Details
- Review your kit - When you receive the test kit in the mail, review its contents, and read through the information provided with the kit.
- This is a urine collection kit that you will collect for at home.
- Do not collect samples while menstruating.
- Do not drink more than 8 oz water 1 hour prior to urine collection.
- Use FedEx to ship samples back to the lab as soon as possible, Monday - Friday only.
Preparation & Timing
- Do not collect samples while menstruating.
- Fasting is not required. However, fasting for 24 hours may increase the excretion of toxic chemicals.
- Please consult your healthcare practitioner prior to fasting.
- Do not drink more than 8 oz water 1 hour prior to urine collection.
Requisition & Payment
- Forms Included with your kit:
- Requisition form: Confirm your information is correct on this form.
- Since your kit has been prepaid, you do not need to fill in the payment information on any of these forms.
- Use the prepaid FedEx shipping envelope to send this back to the lab as soon as possible, Monday - Friday only.
The Vibrant Experience
Vibrant America is a leading science and technology company delivering life-transforming laboratory services using an integrated microarray platform that enables multiplex testing at an affordable cost.
Vibrant’s relationship with its patients and providers is special. We go out of our way to provide the value and resources our providers need to accurately interpret test results and give patients the most accurate health information.
The Most Accurate In the Industry
All tests run on Vibrant’s proprietary 3Dense microchip technology platform boast an unrivaled specificity and sensitivity – which translates to the highest standard of accuracy of results in the lab industry.
Our Lab Technology
Vibrant America is at the forefront of modern medicine. Our technology was developed out of passion for better medicine, and we believe that automation is the key to high-quality and accurate test results. Multiplexing tests on a single sample enable a fast turnaround time.
Our Mission
Dedicated to bring clinically relevant test at a rapid pace to enable affordable high-quality diagnostics to every individual.
- High-quality lab service
- Fully automated systems
- Low cost
- Fast Turn Around Time
Quality and Security
All of our laboratory testings is done in a CLIA and CAP-certified laboratory in California.
Vibrant America's Compliance Overview
